Water Resources Research Act Program

Details for Project ID 2003SC8B

Toxicological Effects of Environmental Pollutants in Lake Constee

Institute: South Carolina
Year Established: 2003 Start Date: 2003-03-01 End Date: 2004-02-28
Total Federal Funds: $21,683 Total Non-Federal Funds: $70,400

Principal Investigators: Peter Van Den Hurk, Stephen Klaine, David Hargett

Project Summary: Lake Conestee is a heavily polluted Superfund (Targeted Brownfields Program) site in the Reedy River watershed, just south of Greenville, SC. The lake, formerly 145 acres, has been silted in to such extent that it now is comprised of about 20 acres of water area, the remainder being emergent wetlands, sloughs, beaver ponds, and wooded bottomland flats. Lake Conestee has received waste water from domestic and industrial sources for over 100 years, as well as runoff from a highly urbanized watershed of 65 sq. miles. The result is a wetlands / aquatic system with high concentrations of nutrients, heavy metals, polyaromatic hydrocarbon pollutants, pesticides and PCBs. Contamination investigations sponsored by U.S.EPA, SCDHEC, and the Corps of Engineers Charleston District have established the nature of contamination of the lake sediments. However, little is know about the dispersion of the contaminants, and even less is known about concentrations and toxicological effects of these contaminants in the organisms in the lake. This has not only caused concern about the environmental health of the system, bioconcentration / biomagnification of certain compounds in the food chain, but also potential effects on human health of people consuming fish, turtles and other game species from the lake. To address the expected toxicological effects, a study is proposed to measure a set of biomarkers in a fish species from the lake. These biomarkers will give insight in how different detoxification pathways are induced, and how severe cellular and subcellular damage has progressed in fish from the lake. This information, combined with chemical, ecological, and whole organisms toxicity data, will enhance the understanding of the extent of the contamination and its effects on biota and provide the foundation for an ecological risk assessment. Further, it will generate data that will be used for human health risk assessment in people using resources in the lake for nutrition and recreation.