State Water Resources Research Institute Program
Project ID: 2009ME171B
Title: Using Fluorescence Spectroscopy as a Rapid, Cost-Effective Method to Monitor and Analyze Low Levels of Pharmaceuticals in Three Maine Rivers.
Project Type: Research
Start Date: 3/01/2009
End Date: 2/28/2010
Congressional District: 2nd
Focus Categories: Water Quality, Toxic Substances, Methods
Keywords: Toxic Substances, Water Chemistry, Water Quality Monitoring
Principal Investigator: Patterson, Howard; Elskus, Adria; Killarney, Jim; LeBlanc, Lawrence A; Peckenham, John
Federal Funds: $ 1,250
Non-Federal Matching Funds: $ 44,826
Abstract: Pharmaceutical compounds are contaminants of emerging concern in U.S. water supplies. Although the concentrations of individual compounds are very low, the sheer numbers of different compounds found are quite large. Very little is known regarding the behavior of these compounds in the water. Additionally, the toxicological effects on human and ecosystem health from chronic exposure to these numerous compounds are poorly understood. There is an evident need for cost-effective, rapid monitoring technologies that can detect pharmaceutical compounds at the low concentrations found in the environment for purposes of modeling and assessment. This study proposes the use of Synchronous Fluorescence Spectroscopy (SFS) and Emission Matrix (EEM) spectroscopy as techniques to identify and characterize pharmaceutical compounds in water samples. Analysis of EEM spectra will be performed using N-way partial lest squares regression-discriminate analysis (NPLS-DA) and parallel factor analysis (PARAFAC). These techniques, if determined robust, provide a cost-effective method of identifying and characterizing, at very low concentrations, exactly what mixture of compounds are present in the water.
Progress/Completion Report, 2009, PDF